Abnormal intrinsic brain functional network dynamics in patients with cervical spondylotic myelopathy

نویسندگان

چکیده

Abstract The specific topological changes in dynamic functional networks and their role cervical spondylotic myelopathy (CSM) brain function reorganization remain unclear. This study aimed to investigate the connection (dFC) of patients with CSM, focusing on temporal characteristics state patterns variability network organization. Eighty-eight CSM 77 healthy controls (HCs) were recruited for resting-state magnetic resonance imaging. We applied sliding time window analysis method K-means clustering capture dFC two groups. graph-theoretical approach was used variance organization whole-brain networks. All participants showed four types states. mean dwell 2 significantly different between Particularly, longer group than control group. Among states, switching relative mainly included executive (ECN), salience (SN), default mode (DMN), language (LN), visual (VN), auditory (AN), precuneus (PN), sensorimotor (SMN). Additionally, properties variable CSM. Dynamic states may offer new insights into intrinsic activities suggest instability

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ژورنال

عنوان ژورنال: Cognitive Neurodynamics

سال: 2022

ISSN: ['1871-4080', '1871-4099']

DOI: https://doi.org/10.1007/s11571-022-09807-0